NFL news roundup: Niners QB Brock Purdy (toe) did not participate in practice; LB Germaine Pratt signs with Colts

INJURIES

• QB Kyler Murray (foot) did not participate in Wednesday's practice.
• WR Zay Jones (knee) limited
• TE Tip Reiman was placed on injured reserve.
• OL Will Hernandez (knee) limited
• OL Jonah Williams (foot) limited
• DL Darius Robinson (pectoral) DNP
• LB Mack Wilson (ankle) limited
• CB Will Johnson (groin) limited

SIGNINGS

• TE Nick Muse (practice squad)

ROSTER CUTS

• S Patrick McMorris (practice squad)

INJURIES

• QB Lamar Jackson (hamstring) did not practice on Wednesday.
• FB Patrick Ricard (calf) DNP
• WR Zay Flowers (shoulder) was a limited practice participant.
• LT Ronnie Stanley (ankle) returned to practice and was limited.
• ILB Roquan Smith (hamstring) DNP
• CB Marlon Humphrey (calf) DNP
• S Kyle Hamilton (groin) returned to practice and was limited.

INJURIES

• RB Chuba Hubbard (calf) did not participate in Wednesday's practice.
• WR Jalen Coker (quadriceps) full
• TE Ja'Tavion Sanders (ankle) limited
• OT Taylor Moton (elbow) DNP
• DT Tershawn Wharton (toe) DNP
• CB Akayleb Evans (hamstring) DNP
• CB Chau Smith-Wade (chest) full
• CB Mike Jackson (ribs) full

INJURIES

• TE Drew Sample (ankle) did not participate in Wednesday's practice.
• G Lucas Patrick (calf) was designated to return from injured reserve and limited at practice.
• DE Shemar Stewart (ankle) limited

OTHER NEWS

• QB Joe Flacco, who was acquired from the Browns on Tuesday, will start in Week 6 against the Packers, head coach Zac Taylor told reporters.

TRADES

• CB Greg Newsome II and a 2026 sixth-round pick are being traded to the Jaguars in exchange for cornerback Tyson Campbell and a '26 seventh-round selection, NFL Network Insiders Ian Rapoport and Tom Pelissero reported.

SIGNINGS

• CB Dom Jones signed to active roster from practice squad
• CB Dee Williams (practice squad)

INJURIES

• TE David Njoku (knee) was a full participant in Wednesday's practice.
• C Ethan Pocic (neck) limited
• DE Myles Garrett (ankle) limited
• CB Greg Newsome II (hamstring) limited
• CB Ameer Speed placed on practice squad/injured reserve.
• CB Denzel Ward (hip) limited

INJURIES

• RB Miles Sanders (knee/ankle) was limited in Wednesday's practice.
• WR CeeDee Lamb (ankle) DNP
• WR KaVontae Turpin (foot) did not practice and told reporters it's unlikely he'll play Sunday against the Panthers.
• LT Tyler Guyton (concussion) limited
• G Tyler Booker (ankle) DNP
• G Tyler Smith (knee) limited
• DE Jadeveon Clowney (hip) limited
• DE James Houston (knee) limited
• DE Marshawn Kneeland (ankle) limited
• CB Trevon Diggs (knee) limited
• S Donovan Wilson (elbow/knee) DNP

INJURIES

• RB Tyler Badie (shoulder) was limited in Wednesday's practice.
• G Ben Powers (biceps) DNP
• DT D.J. Jones (shoulder) limited 
• DT Malcolm Roach has been designated for return from injured reserve and was limited.
• OLB Nik Bonitto (wrist) full
• OLB Jonah Elliss (ribs/shoulder) DNP
• ILB Alex Singleton (thumb) full

SIGNINGS

• OL Dan Skipper (practice squad to active roster)
• CB Arthur Maulet is signing with Detroit's practice squad, NFL Network's Cameron Wolfe reported, per a source. The team later announced the signing.

INJURIES

• CB Khalil Dorsey (wrist) was placed on injured reserve.

INJURIES

• QB Jordan Love (left thumb/ankle) was a full participant in Wednesday's practice.
• WR Christian Watson (knee) limited
• TE Tucker Kraft (elbow) full
• OT Anthony Belton (ankle) DNP
• OT Jordan Morgan (knee) full
• OT Zach Tom (oblique) limited
• OT Rasheed Walker (quadricep) limited
• G Aaron Banks (groin) limited
• K Brandon McManus (right quadricep) limited

SIGNINGS

• LB Germaine Pratt is signing a one-year contract, NFL Network Insiders Ian Rapoport and Tom Pelissero reported. Four additional teams had interest in Pratt, who was released by the Raiders on Monday, but Pratt decided to reunite with his former defensive coordinator, Lou Anarumo.

INJURIES

• RB Tyler Goodson (groin) did not participate in Wednesday's practice.
• WR Alec Pierce (concussion) full
• DT Grover Stewart (biceps) full
• DE Tyquan Lewis (illness) DNP
• LB Joe Bachie (quad) was placed on injured reserve.
• CB Kenny Moore (Achilles) DNP

TRADES

• CB Tyson Campbell and a 2026 seventh-round pick are being traded to the Browns in exchange for cornerback Greg Newsome II and a 2026 sixth-round pick, NFL Network Insiders Ian Rapoport and Tom Pelissero reported.

INJURIES

• RB Bhayshul Tuten (shoulder) was limited in Wednesday's practice.
• WR Dyami Brown (shoulder) limited
• OL Ezra Cleveland (ankle) limited
• OL Anton Harrison (elbow) limited
• DE Travon Walker (wrist) limited
• S Eric Murray (neck) limited
• P Logan Cooke (persona) DNP

SIGNINGS

• RB Cody Schrader (active roster)
• TE Qadir Ismail (practice squad)

INJURIES

• QB Patrick Mahomes (groin) was a full participant in Wednesday's practice.
• RB Kareem Hunt (calf) full
• WR Marquise Brown (ankle) full
• WR JuJu Smith-Schuster (knee) full
• WR Xavier Worthy (shoulder/ankle) full
• OT Jawaan Taylor (knee) full
• DE Charles Omenihu (ankle) full
• LB Nick Bolton (calf) full

INJURIES

• TE Brock Bowers (knee) did not participate in Wednesday's practice.
• TE Michael Mayer (concussion) full
• G Jackson Powers-Johnson (ankle) full
• DE Maxx Crosby (knee) full
• CB Eric Stokes (knee) limited
• P AJ Cole (right ankle) DNP

SIGNINGS

• LB Jamin Davis (practice squad)
• LB Jon Rhattigan (active roster)

ROSTER CUTS

• QB Jeff Driskel

INJURIES

• RB Omarion Hampton (ankle) was officially placed on injured reserve.
• WR Quentin Johnston (hamstring) was limited in Wednesday's practice.
• OT Joe Alt (ankle) DNP
• G Mekhi Becton (hand) limited
• G Trey Pipkins (knee) DNP
• DL Da'Shawn Hand (groin) DNP
• OLB Bud Dupree (hamstring)
• LB Denzel Perryman (ankle) limited

SIGNINGS

• RB Nyheim Hines (practice squad)
• RB Kimani Vidal (practice squad to active roster)

INJURIES

• TE Tyler Higbee (hip) did not participate in Wednesday's practice.
• TE Colby Parkinson (concussion) limited
• OL Rob Havenstein (ankle) DNP
• ILB Nate Landman (ankle) limited
• ILB Omar Speights (ankle) DNP
• S Kamren Kinchens (knee) limited

INJURIES

• QB Tua Tagovailoa (hip/left thumb) was limited in Wednesday's practice.
• WR Ced Wilson (knee) limited
• TE Darren Waller (hip/rest) DNP
• OL Larry Borom (thumb) limited
• OL Aaron Brewer (pectoral) limited
• CB Cornell Armstrong (hamstring) was placed on injured reserve.
• CB Storm Duck (ankle) limited
• DB Elijah Campbell (quadricep) limited

SIGNINGS

• CB Kendall Sheffield (practice squad)
• S Jordan Colbert (practice squad to active roster)

SIGNINGS

• G Vershon Lee (practice squad)

INJURIES

• G Mike Onwenu (shoulder/thigh) was a full participant in Wednesday's practice.
• DT Christian Barmore (non-injury relate/other) limited
• DT Milton Williams (ankle) limited
• DE Keion White (elbow) DNP
• LB K'Lavon Chaisson (knee) limited
• LB Anfernee Jennings (ankle) limited
• S Jaylinn Hawkins (hamstring) DNP

INJURIES

• RB Alvin Kamara (ankle) was limited after injuring his ankle in Wednesday's practice, head coach Kellen Moore said. Moore said the injury isn't a concern.
• TE Juwan Johnson (ankle) limited
• OT Trevor Penning (ankle) limited
• C Cesar Ruiz (ankle) limited
• DE Chase Young (calf) limited
• S Justin Reid (concussion protocol) limited

INJURIES

• WR Darius Slayton (hamstring) was ruled out for Thursday's game against the Eagles.
• OT Jermaine Eluemunor (back) is questionable for Week 6.
• LB Swayze Bozeman (ankle) out
• LB Demetrius Flannigan-Fowles (hamstring) out

INJURIES

• QB Justin Fields (knee) was a full participant in Wednesday's practice.
• RB/KR Kene Nwangwu (hamstring) DNP
• WR Allen Lazard (personal) will not play Sunday against the Broncos in London, Aaron Glenn told reporters.
• DE Jermaine Johnson II (ankle; DNP) is day to day with an ankle injury but trending toward returning Sunday against Denver, Glenn said.
• DT Quinnen Williams (groin) limited
• LB Ja’Markis Weston was designated to return from injured reserve.
• CB Michael Carter II (concussion; DNP) did not make the trip to London and is likely out on Sunday, per Glenn.

INJURIES

• TE Grant Calcaterra (oblique) was ruled out for Thursday's game against the Giants.
• G Landon Dickerson (ankle) out
• DT Jalen Carter (heel) questionable
• LB Nakobe Dean (knee) questionable

INJURIES

• RB Jaylen Warren (knee) was a full participant in Wednesday's practice.
• WR Calvin Austin III (shoulder) DNP
• WR Ben Skowronek (illness) limited
• LB Alex Highsmith (ankle) limited
• CB Joey Porter Jr. (hamstring) full
• CB Jalen Ramsey (hamstring) DNP

INJURIES

• QB Mac Jones (knee/oblique) was limited in Wednesday's practice.
• QB Brock Purdy (toe) DNP
• WR Kendrick Bourne (rib) full
• WR Jauan Jennings (ankle/ribs) DNP
• WR Ricky Pearsall (knee) DNP
• DL Kevin Givens had his 21-day window practice open, the team announced.
• DL Yetur Gross-Matos (pectoral) DNP
• CB Upton Stout (ankle) limited
• P Thomas Morstead (back) full

SIGNINGS

• DL Bruce Hector (practice squad)

ROSTER CUTS

• S Jalen Mahoney (practice squad)

INJURIES

• G Shane Lemieux was placed on practice squad injured reserve.
• LB Derick Hall (oblique) did not participate in Wednesday's practice.
• LB Ernest Jones (shoulder) DNP
• LB Demarcus Lawrence (quadricep) DNP
• CB Devon Witherspoon (knee) DNP
• CB Tariq Woolen (concussion) limited
• S Nick Emmanwori (ankle) limited
• S Julian Love (hamstring) DNP

SIGNINGS

• S Maxen Hook (practice squad)

INJURIES

• RB Bucky Irving (foot/shoulder) did not participate in Wednesday's practice.
• WR Mike Evans (hamstring) DNP
• WR Chris Godwin (fibula) DNP
• OT Tristan Wirfs (knee) limited
• LB Lavonte David (knee) limited
• CB Zyon McCollum (thumb) DNP
• CB Jamel Dean (hip) limited

SIGNINGS

• RB Owen Wright (practice squad)

ROSTER CUTS

• G Sua Opeta (practice squad)

INJURIES

• RB Tyjae Spears (ankle) was limited in Wednesday's practice.
• WR Van Jefferson (ankle) DNP
• OT JC Latham (hip) limited
• DT Jeffery Simmons (ankle) DNP
• K Joey Slye (right calf) DNP

SIGNINGS

• K Matthew Wright (practice squad)

INJURIES

• WR Noah Brown (knee/groin) will participate in Wednesday's practice, head coach Dan Quinn told reporters.
• WR Terry McLaurin (quad) will not participate, per Quinn.