NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

It's only early June, but the injury bug has already arrived in Santa Clara. Two 49ers, offensive lineman Justin Skule and defensive back Tarvarius Moore, suffered significant injuries during Monday's OTAs session.

Jimmy Garoppolo enjoyed a terrible, horrible, no good, very bad day at the office on Wednesday afternoon. During one stretch of practice, the 49ers starting quarterback threw five consecutive interceptions.

Could Jay Ajayi make a difference for the Colts? Should Eric Berry reunite with John Dorsey in Cleveland? Gil Brandt finds the best team fits for the top remaining free agents.

Last season, the San Francisco 49ers allowed the second-most touchdowns through the air. Nevertheless, Richard Sherman believes the team's defensive secondary will be fine.

Which NFL team enjoyed the best rookie class in 2018? The worst? Jeremy Bergman and Nick Shook teamed up to rank every single group, from 1 to 32.

Jeremy Bergman turns a critical eye toward the rookie classes of each team in the NFC West. Does the Cardinals' future look bright? Should the Seahawks regret their first-round choice?

The Cleveland Browns were able to sweep the Cincinnati Bengals in a season for the first time since 2002. Here's what else we learned from Sunday's Week 16 games.

It's dress rehearsal week in the NFL as teams get ready for the start of the NFL season. Who will take center stage? Here's what to watch for in Week 3 of the preseason.

San Francisco 49ers strong safety Tarvarius Moore secures a juggling interception in the end-zone against Houston Texans quarterback Davis Mills.

Watch highlights from the Week 15 matchup between the San Francisco 49ers and the Dallas Cowboys.

Watch the Buffalo Bills vs. San Francisco 49ers highlights from Week 13 of the 2020 season.

Watch the highlights of the Week 10 matchup versus the San Francisco 49ers and the New Orleans Saints.

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Watch the best defensive plays from the San Francisco 49ers in their Week 7 matchup against the New England Patriots.

Watch the highlights from Super Bowl LIV between the San Francisco 49ers and the Kansas City Chiefs.

Check out the San Francisco 49ers defense's best plays from Super Bowl LIV against the Kansas City Chiefs.

San Francisco 49ers cornerback Tarvarius Moore picks off Kansas City Chiefs quarterback Patrick Mahomes.

Watch complete highlights from the Week 16 matchup between the Chicago Bears and San Francisco 49ers.