As the San Francisco 49ers return from a bye week, they hold tight to an undefeated record and the top spot in the NFC West.
It is through Seattle and Los Angeles that the division has gone in seasons of late, however.
Here are four things to watch for on TNF:
1. The curious case of Jared Goff
Somewhere in the middle of being a Goff apologist and a Goff detractor is likely where the good, bad and ugly realistically resides for the former No. 1 overall pick.
Goff threw for myriad career-highs such as 45 completions, 68 attempts and 517 yards, but he had four turnovers, including a lost fumble that expunged any hopes of a Rams comeback.
All the pressure cannot fall squarely on the signal-caller's shoulders as he's been pressured 64 times, according to Next Gen Stats, which is more than any other quarterback. Still, when you drop back that many times, the pressure is going to come.
Thursday provides another prime-time showcase for McVay's offense to find its former dazzling form and sustain it on a consistent basis.
2. Russell Wilson's quiet stellar start
Wilson is off to one of his finest starts so far.
His numbers are brilliant: 97-for-133 for 1,141 yards, a 72.9 completion percentage, eight touchdowns and zero interceptions.
However, Wilson's wonderful start will collide with his most dreadful opponent.
Will Wilson shake up his past storyline or will the Rams' defense, coming off a dismal defensive effort, continue to bottle up one of the league's premier passers?
3. Bobby Wagner continues his tremendous tackling ways
Sometimes a storyline becomes such a standard that it's overlooked no matter how standard.
He is a tackling instrument that has never dulled, wavered or shirked a task at hand. Since 2012, Wagner has racked up 959 tackles -- second only to the equally impressive Luke Kuechly in Carolina.
A five-time Pro Bowl pick and four-time All-Pro, Wagner's averaging more than 10 tackles per outing this season with 45, which is tops on his team and third in the NFL.
Wagner's play in the middle is something special to behold and likewise crucial to the Seahawks' success. In the Seahawks' lone loss to the Saints in Week 3, Wagner was all over the place and turned in a career-high 19 takedowns. Wagner is likely to lead the defense win or lose, but the Seahawks' D is at its best when everyone is contributing.
4. Is it past due for Aaron Donald to have a big game?
Many believe the reigning NFL Defensive Player of the Year is the best overall player in the league.
With that attention comes game-planning and Donald draws double-teams, triple-teams and respect and attention from the opposition. With all that, production can waver though you're still impacting a game by freeing up your teammates.
Such is the case with Donald, but he has yet to break out this season.
So far, he has only one sack through four weeks and 12 tackles.
Rams fans can find solace in the fact that he only had two sacks through four games a season ago. And, he has 10.5 sacks and 28 QB hits in his career against Wilson, which are his best numbers against any QB.