Wednesday's NFL injury and roster news for Week 10

Christian McCaffrey won't be on the field today ... or this Sunday.

The Carolina Panthers running back won't practice Wednesday as he deals with a painful shoulder injury and has already been ruled out for Sunday's game against the Tampa Bay Buccaneers, NFL Network Insider Ian Rapoport reported. Rapoport added McCaffrey is getting a second opinion on his hurt shoulder.

Panthers coach Matt Rhule later told reporters that McCaffrey specifically is dealing with an AC joint issue in his shoulder and he "probably" won't play this weekend. Rhule did, however, note that he does not anticipate this injury ending McCaffrey's season, and the team plans to take CMC's status week by week.

McCaffrey suffered the injury late in Sunday's close loss to the Kansas City Chiefs. The running back was slammed hard to the turf and was clearly in pain on the sideline during subsequent plays. He returned for the Panthers' final plays.

Rapoport reported earlier this week that the shoulder injury could force CMC to miss more time after he recently returned after sitting out six weeks due to a high-ankle sprain.

With McCaffrey unable to suit up Sunday, Mike Davis is in line to regain his sizable workload. Receiver Curtis Samuel could also see additional backfield snaps, where he's seen increasing usage in recent weeks.

Here's other injuries and roster news we're tracking on Wednesday:

• Miami Dolphins wideout Preston Williams will be placed on injury reserved with his foot injury, coach Brian Flores told reporters. His injury is a little more significant than they thought, he stated. Running back Matt Breida was limited at practice.
• The Baltimore Ravens have activated cornerback Marlon Humphrey from the reserve/COVID-19 list, the team announced. Running back Mark Ingram (ankle) was limited at practice. Linebacker Matt Judon (calf) and defensive end Calais Campbell (calf) did not participate.
• Houston Texans coach Romeo Crennel said running back David Johnson, who left Sunday's game with a concussion, will probably not practice today.
• Washington Football team running back Bryce Love is returning to practice after dealing with a knee injury.
• The Arizona Cardinals activated linebacker Devon Kennard and cornerback Byron Murphy from the reserve/COVID-19 list. Arizona also signed cornerback Johnathan Joseph, placed cornerback Kevin Peterson (concussion) on injured reserve and designated defensive lineman Rashard Lawrence and offensive lineman J.R. Sweezy to return from IR. Running back Kenyan Drake (ankle) returned to practice.
• The Cincinnati Bengals activated linebacker Jordan Evans and cornerback Mackensie Alexander from the reserve/COVID-19 list. The team later announced Alexander was held out of practice due to an illness. Cincinnati also designated guard Xavier Su'a-Filo to return from injured reserve. Running back Joe Mixon did not participate in team drills today, coach Zac Taylor said. The Bengals claimed defensive end Takkarist McKinley off waivers.
• Los Angeles Chargers coach Anthony Lynn said defensive end Joey Bosa will participate in individual drills today, but he's still in the concussion protocol.
• New York Giants running back Devonta Freeman (ankle) and receiver Sterling Shepard (toe/hip) were limited in practice.
• The Indianapolis Colts have placed linebacker Matthew Adams on the reserve/COVID-19 List. Wideout T.Y. Hilton (groin) is off the injury report and will play vs. the Titans. Tight end Jack Doyle (concussion) has been ruled out. Tight end Mo Alie-Cox (knee) is questionable.
• The San Francisco 49ers announced they have promoted running back Austin Walter to the active roster from the team's practice squad and placed safety Jaquiski Tartt on the injured reserve List. The team also signed quarterback Josh Johnson to the team's practice squad. Running back Tevin Coleman (knee) and wide receiver Deebo Samuel (hamstring) did not practice on Wednesday.
• The Tennessee Titans activate cornerback Adoree' Jackson from injured reserve and placed safety Dane Cruikshank on IR. Jackson won't play against the Colts on Thursday.
• The Seattle Seahawks signed running back Bo Scarbrough to their practice squad. Coach Pete Carroll told reporters that there was a good chance defensive tackle Damon Harrison would make his Seahawks debut this week. Harrison was signed to the team's practice squad on Oct. 7. Running back Chris Carson (foot), defensive end Benson Mayowa (ankle), running back Carlos Hyde (hamstring), linebacker K.J. Wright (ankle), cornerback Shaquill Griffin (concussion/hamstring) did not practice.
• Los Angeles Rams coach Sean McVay said wideout Cooper Kupp will be limited at practice but will likely play vs. the Seahawks. Running back Darrell Henderson (quad) did not practice.
• Jacksonville Jaguars quarterback Gardner Minshew (right thumb) did not practice.
• Pittsburgh Steelers wideout JuJu Smith-Schuster (knee) did not practice.
• The Kansas City Chiefs placed wideout Mecole Hardman on the reserve/COVID-19 list, per the transaction wire.
• The Dallas Cowboys placed defensive end Tyrone Crawford on the reserve/COVID-19 list, per the transaction wire.
• New Orleans Saints QB Drew Brees (right shoulder), WR Michael Thomas (ankle/hamstring), C Erik McCoy (elbow) and OT Ryan Ramczyk (back) were limited in Wednesday's practice.
• Las Vegas Raiders fullback Alec Ingold suffered two broken ribs on Sunday, but plans to play through the injury in Week 10 against the Denver Broncos, NFL Network Insider Ian Rapoport reported, per a source.