Top defensive plays | Week 5

Watch the top defensive plays from Week 5 of the 2025 NFL season.

Watch the top plays from Week 5 during the 2025 NFL season.

Watch the best plays by Jacksonville Jaguars quarterback Trevor Lawrence from his 275-yard, 3-TD game during Week 5 of the 2025 NFL season.

Highlights from the Week 5 matchup between the Kansas City Chiefs and the Jacksonville Jaguars during the 2025 NFL season.

Watch the top runs from Week 5 of the 2025 NFL season.

Watch the top touchdowns from Week 5 of the 2025 NFL season.

Watch the top catches from Week 5 during the 2025 NFL season.

Watch Kansas City Chiefs quarterback Patrick Mahomes' best plays from his 378-yard game vs. the Jacksonville Jaguars in Week 5 of the 2025 NFL season.

Jacksonville Jaguars quarterback Trevor Lawrence falls twice after the sack and stumbles into the endzone for a go-ahead touchdown against the Kansas City Chiefs.

Kansas City Chiefs running back Kareem Hunt rushes for a 2-yard touchdown for his second of the game.

Kansas City Chiefs quarterback Patrick Mahomes locates wide receiver Marquise Brown for a 20-yard tippy toe catch.

Jacksonville Jaguars quarterback Trevor Lawrence drops a perfect pass through a narrow window into the hands of wide receiver Brian Thomas Jr.

Kansas City Chiefs quarterback Patrick Mahomes scrambles out of pocket pressure for a 5-yard first down.

Kansas City Chiefs running back Kareem Hunt hurdles a Jacksonville Jaguar for 6 yards, but is smacked down by safety Andrew Wingard.

Jacksonville Jaguars kicker Cam Little nails a 52-yard field goal.

Kansas City Chiefs running back Kareem Hunt rushes for a 5-yard touchdown to cap quick two-play drive against the Jacksonville Jaguars.

Kansas City Chiefs cornerback Trent McDuffie intercepts Jacksonville Jaguars quarterback Trevor Lawrence.

Kansas City Chiefs quarterback Patrick Mahomes locates wide receiver Xavier Worthy for a 19-yard gain.

Kansas City Chiefs running back Isiah Pacheco barrels through the Jacksonville Jaguars defense for an 11-yard gain.

Jacksonville Jaguars linebacker Devin Lloyd jumped the route perfectly and intercepts Kansas City Chiefs quarterback Patrick Mahomes for a coast to coast pick-six.

Jacksonville Jaguars quarterback Trevor Lawrence finds a hole in the Kansas City Chiefs defense for a 10-yard rushing touchdown on his 26th birthday.

Jacksonville Jaguars rookie wide receiver Travis Hunter gets air and outlasts two Kansas City Chiefs defenders to reel in 44-yard pass from quarterback Trevor Lawrence.

Jacksonville Jaguars quarterback Trevor Lawrence connects with wide receiver Parker Washington for a 3-yard touchdown.

Jacksonville Jaguars wide receiver Travis Hunter stutter steps to evade tackle for 12-yard catch and run off a pass from quarterback Trevor Lawrence.

Kansas City Chiefs quarterback Patrick Mahomes throws a deep ball to Tyquan Thornton who is wide open for a 34-yard gain.