Andy Isabella spikes ball after diving effort gives him second TD of day

Watch the best moments from Peyton and Eli Manning and their guests during the Seattle Seahawks-New York Giants Week 4 matchup.

Watch all of the top rookie plays from Week 4 of the NFL season.

Watch the top defensive plays from Week 4 of the 2023 NFL season.

Watch the top runs during Week 4 of the 2023 NFL season.

Watch the top touchdowns during Week 4 of the 2023 NFL season.

Watch top plays from Week 4 during the 2023 NFL season.

Watch the Seattle Seahawks' best defensive plays from their Week 4 game against the New York Giants.

Watch the highlights from the Week 4 matchup between the Seattle Seahawks and the New York Giants.

Seattle Seahawks linebacker Boye Mafe, who lost his mother to cancer on Mother's Day, says "I love you" in sign language before game during "Monday Night Football".

Seattle Seahawks linebacker Uchenna Nwosu's second sack of New York Giants quarterback Daniel Jones increases the Seahawks' count to 11.

Seattle Seahawks defensive lineman Myles Adams' first sack of 2023 is the Seahawks ninth of New York Giants quarterback Daniel Jones.

New York Giants linebacker Kayvon Thibodeaux drops Seattle Seahawks quarterback Geno Smith for his second sack of the night.

Seattle Seahawks running back Kenneth Walker III hits the hole hard on a 31-yard run.

Seattle Seahawks defensive back Quandre Diggs logs his first interception of the 2023 season late in the fourth quarter of 'Monday Night Football.'

New York Giants quarterback Daniel Jones escapes up the middle of the Seattle Seahawks defense for a 17-yard gain.

Seattle Seahawks linebacker Uchenna Nwosu can't be stopped on the Seahawks' eighth sack of the night on New York Giants quarterback Daniel Jones.

Seattle Seahawks linebacker Bobby Wagner notches his second sack of New York Giants quarterback Daniel Jones.

Seattle Seahawks defensive back Devon Witherspoon undercuts a throw by New York Giants quarterback Daniel Jones and returns it 97 yards for a pick-sic touchdown.

New York Giants quarterback Daniel Jones converts a 4th-and-short with a 10-yard bootleg scramble.

A 53-yard field goal from Seattle Seahawks kicker Jason Myers flies wide left.

Seattle Seahawks linebacker Bobby Wagner loops around the edge for a sack of New York Giants quarterback Daniel Jones.

Seattle Seahawks running back Zach Charbonnet has a wide open hole to run through for 15 yards.

Seattle Seahawks running back Kenneth Walker III slithers through a seam in the line of scrimmage for a 16-yard rush.

Seattle Seahawks quarterback Geno Smith lofts a 23-yard pass to wide receiver Tyler Lockett.

Seattle Seahawks running back Kenneth Walker III powers across the goal line for a 1-yard touchdown to extend the Seahawks lead over the New York Giants to 13-3.