The Los Angeles Rams will be without a critical member of their defense for Monday night's big battle with the Arizona Cardinals.
The team announced Monday that cornerback Jalen Ramsey has been placed on the reserve/COVID-19 list.
Tight end Tyler Higbee was also placed on the reserve/COVID-19 list. That brings the Rams' total to five, as the team placed running back Darrell Henderson, right tackle Rob Havenstein and cornerback Donte' Deayon on the list over the weekend.
With Ramsey out, it completely changes how the Rams can line up against Nuk and the rest of the Cards wideouts.
Among 14 players with 10-plus targets in coverage on Hopkins since 2016 (when Ramsey was drafted), Ramsey's passer rating allowed of 76.9 is third-lowest, per Next Gen Stats.
In Week 4, only 28.6 percent of Hopkins' routes came when lined up against Ramsey, and 60.0 percent came against Darious Williams, via NGS. Hopkins had one catch on three targets for 18 yards while covered by Ramsey that week.
Monday night's game is pivotal for both clubs in the race for playoff seeding. If the Cardinals win, they clinch a postseason berth, retain the NFC's top seed and take a three-game lead in the NFC West. A Rams victory would pull them to within a game of Arizona in the division with four to play.