"There's no give-up in our guys," said Borland, who had two of the five interceptions by the 49ers (6-4). "We have guys, veterans, who have been there a lot. When it was going tough, we just pressed on and kept looking forward. Back-to-back wins on the road, we're all excited."
It should have been a lot easier. San Francisco had almost 35 minutes in time of possession and five takeaways, but it had to sweat out a first-and-goal from its 4 to win.
"It was a spectacular performance by our defense today," San Francisco coach Jim Harbaugh said. "So many guys stepped up and played great, living in the moment and competing like the dickens and making tremendous and athletic football plays."
Manning threw a 19-yard touchdown pass to tight end Larry Donnell on New York's opening possession, but the Giants (3-7) only got a field goal from Josh Brown the rest of the way. After throwing six interceptions in the Giants' first nine games, Manning nearly equaled that number while tying a single-game career high against the 49ers.
"We made it hard for him," Smith said of Manning, who was hit twice by the linebacker. "Making him uncomfortable in the pocket and moving him around, pressuring him from everywhere."
New York had a chance to take the lead earlier in the quarter, driving to the San Francisco 32. On a second-and-5, Manning and his receiver seemed a little out of synch and Chris Culliver intercepted the pass near the 10.
"I have to make better throws," said Manning, who finished 22 of 45 for 280 yards. "It's no one else's fault. I've got to protect the ball and not turn it over. I turned it over close a couple of times and that can't happen."
After three field goals by Dawson, San Francisco stretched the lead to 16-7 early in the third quarter when Kaepernick (15 of 29 for 193 yards) found Crabtree across the middle and the receiver outran five defenders for a 48-yard catch-and-run.
"We're trying to take advantage of the opportunities that we have," Kaepernick said. "We know our backs are against the wall. We have to play every week like it's our last game."
Brown narrowed the gap to 16-10 with a 43-yard field goal midway through the third quarter and New York seemingly got a boost when it recovered the ensuing onside kick. However, the offense faltered and New York did not make the plays down the stretch.
NOTES: Randle led the Giants with seven catches for 112 yards, while Beckham had six for 93 yards. ... Giants halfback Rashad Jennings played for the first time since spraining his knee in early October and had 59 yards on 18 carries. ... Borland had a team-high 12 tackles and also defended three passes. ... Giants LB Jameel McClain had a game-high 14 tackles. ... Borland and Wilhoite are the first two 49ers linebackers to make interceptions in the same game since Nov. 12, 1995, when Rickey Jackson and Lee Woodall did it against Dallas.
Copyright 2014 by The Associated Press